I kind of like the f-word. I try not to use it a lot myself, but I certainly don't mind when others use it in a clever way.
I don't like when people self-edit in a lame way. Grey's Anatomy is a chief offender. Every time a character yells, "Screw it!" all I can think about is the fact that a real doctor in a genuine life-or-death situation would probably just drop the f-bomb or say nothing at all. As my con law professor once said, "'Screw the draft' just doesn't have the same punch as 'F**k the draft.'"
The fact is, that word has a specific meaning, even if that meaning is hard to express otherwise. Like describing the taste of salt to a person who has never tried it--there's really no other word but "salty." When the f-word is appropriate, nothing else will do and you won't know why until you really, really need it.
Like yesterday, when I rubbed my eyes, forgetting that I had just crushed some dried arbol chiles, at which point I let out such a chorus of f-words that I'm surprised a representative from the Mormon Tabernacle Choir didn't promptly knock on my door and offer me a solo on their next CD.